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Dr. Ana Hernandez

03/89-10/89: Grant supported by the Word Health Organization (WHO) to work in the molecular pathways involved in the chronic myeloid leukemia and acute lymphocytic leukemia at the Institute of Cancer Research in London, United Kingdom.









University of Havana, Havana, Cuba

Bachelor in Sciences


Biochemistry/Molecular Biology

Institute for Cancer Research, London, UK

Institute for Medical Science of Havana, Havana, Cuba





Molecular Biology

Medical Sciences

Heinrich-Heine University, Dusseldorf, Germany  





University of Miami, Miami, USA





A. Personal Statement

My research interests involve the fields of immunology, cellular and molecular biology. My research experience provided me with a vast knowledge in multiple areas including molecular biology, cellular Immunology, stem cell technology and flow cytometry. After I finished my Bachelor’s degree I started to work on the molecular pathways implicated in the development of leukemia and lymphoma diseases. During that period, I acquired a strong background in the mechanisms leading to B and T cell rearrangements and basic methodologies in molecular biology. I started my Ph.D at the Cancer Research in London, United Kingdom where I studied the role of alternative splicing patterns of BCR/ABL trancripts in the generation of the blast crisis of chronic myeloid leukemia. I finished these studies at the University of Dusseldorf, Germany. For my postoctoral training I worked on the culture of human mesenchymal stem cells derived from bone marrow or cord blood and their differenciation into cardiomyocytes. I continues my post doctoral training at the University of Miami where I had the opportunity to acquire a better understanding of the processes involved in generation of immune tolerance after transplantation. After I finished my post-doc, I focused my research on the immune monitoring of patients after transplant to understand the mechanisms of graft tolerance. I was also involved in the immunemonitoring of animal model to assess the effect of mesenchymal stem cells (MSC) on allogeneic transplant which included the expansion of MSC from Bone Marrow and Characterization of MSC by phenotypic analysis and functional assays. One of my major interest is in the field of regenerative medicine where stem cells have been successfully use in the treatment of multiples medical conditions.    

B. Positions  

  • 09/84-04/92: Research Associate. Institute of Hematology and Immunology, Molecular Biology Department, Havana, Cuba.
  • 05/92-05/93: Scientist. Institute of Neuropathology, Heinrich-Heine University, Dusseldorf, Germany.  
  • 06/93-05/99: Scientist. Institute of Transplantation and Cell Therapies, Heinrich-Heine University, Dusseldorf, Germany.
  • 07/01-02/03: Scientist. Kourion Therapeutics AG, Dusseldorf, Germany.
  • 03/03-12/06: Post-Doc. Department of Surgery, Division of Transplantation, University of Miami, USA.
  • 01/07-05/16: Associate Scientist. Diabetes Research Institute, University of Miami, USA
  • 06/16-Present: Miami Research Associates (MRA), Miami, Fl (private company)


03/89-10/89: Grant supported by the Word Health Organization (WHO) to work in the molecular pathways involved in the chronic myeloid leukemia and acute lymphocytic leukemia at the Institute of Cancer Research in London, United Kingdom.  


  • Contribution to Science

The list of peer reviewed publications listed below is a reflection of my contribution to these fields of science.  

Selected Publications (in descendent chronological order)

  • Kenyon NS, Willman MA, Han D, Hernandez A, Rabassa A, Diaz A, Geary JC, Kenyon NM, Bartholomew

A, McHenry K, Salomon D and Berman DM. Mesenchymal Stem Cells Enhance Rejection Free and Overall Islet Allograft Survival (This work has been accepted for oral presentation at the 2015 American Transplant Congress (ATC) at the Pennsylvania Convention Center, May 2-6, 2015).

  • Hernandez A, Han D, Oberholzer J, Ricordi C, Alejandro R, Kenyon NS. Effect of lysofylline on the immune response in islet transplant patients (abstract). J Clinical Immunology. 33 (3), 692, 2013. (This work has been accepted as a poster presented in Clinical Immunology Society Annual Meeting, April 25-28, 2013, Miami, FL, poster #1).
  • Hernandez A, Burger M, Blomberg BB, Ross WA, Gaynor JJ, Lindner I, Cirocco R, Mathew JM, Carreno M, Jin Y, Lee KP, Esquenazi V, Miller J.: Inhibition of NF-kappa B during human dendritic cell differentiation generates anergy and regulatory T-cell activity for one but not two human leukocyte antigen DR mismatches. Hum Immunol. 68, 715, 2007.
  • Strauer BE, Brehm M, Zeus T, Kostering M, Hernandez A, Sorg RV, Kogler G, Wernet P. :Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans. Circulation. 2002 Oct 8;106 (15):1913-8.
  • Strauer,B.E; Brehm, M; Zeus, T; Gattermann, N; Hernandez, A; Sorg, R.V; Kögler, G; Wernet, P.: Myocardial regeneration after intracoronary transplantation of human autologous stem cells following acute myocardial infarction. Deutsche Medicinische Wochenschr. 126: 932-938, 2001  
  • Hernández, A.; Meyer, A.; Enczmann, J.; Ackermann, R.; Wernet, P.: Establishment of experimental conditions for the rapid detection of mutations in the VHL gene by parallel temeprature gradient gel electrophoresis. Electrophoresis 20, 1958,1999.
  • Hernández, A.; Zöller, K.; Enczmann, J.; Ebert, T.; Schmitz-Draeger, B.; Ackermann, R.; Wernet, P.: Differential transfection efficiency rates of the GM-CSF gene into human renal carcinoma cell lines by lipofection. Cancer Gene Therapy 4, 59, 1997 .
  • Wenzel, M., Enczmann, J., Uhrberg, M, Hernandez, A., Wiese, U., Ackermann, R., Ebert, T.; SchmitzDraeger, Wernet, P.: Screening for renal carcinoma associated mutations in the von Hippel- Lindau tumor suppressor gene by temperature gradient gel electrophoresis. Electrophoresis 18: 45, 1997.
  • Kögler, G.; Hernández, A.; Heyll, A.; Wolf H.H.; Wernet, P.: Qualitative assessment of mixed chimerism after bone marrow transplantation with regard to leukemic relapse. Cancer Detection and Prevention 20: 601, 1996 .
  • Hernández, A.; Uhrberg, M.; Enczmann, J.; Witt, I.; Reitsma, P.H.; Wernet, P.: Rapid identification of gene defects in protein C deficiency by temperature gradient gel electrophoresis. Blood Coagulation and Fibrinolysis 6, 23, 1995.
  • Hernández, A.; Magario,C; Gispert,S.; Santos,N.; Lunkes,A.; Orozco, G.; Heredero,L.; Beckmann,J.; Auburger, G.: Genetic mapping of the spinocerebellar ataxia 2 (SCA 2) locus on chromosome 12q23-q24.1. Genomic 25, 433, 1995
  • Hernández,A.; Hernández,P.; Corral,L.; Muñiz,A.; Aláez,C.; Espinosa,E.; Fernández,O.; Martínez,G.: p53 gene rearrangements in chronic myelocytic leukemia. Ann. Hematol 66:81, 1993.
  • Silveira, I.; Manaia, A.; Melki, J.; Magarino, C.; Lunkes, A.; Hernandez, A.; Gispert, S.; Burlet, P.; Rozet, J.M.; Coutinho, P.; Auburger, G.: Machado-Joseph disease is genetically different from Holguin dominant ataxia (SCA2). Genomics 17: 556, 1993.
  • Gispert,S.; Twells,R.; Orozco,G.; Brice, A.; Weber,J.; Heredero,L.; Scheufler,K.; Riley,B.; Allotey,R.; Northers,C.; Hillermann,R.; Lunkes,A.; Khati,C.; Stevanin,G.; Hernández,A.; Magarino,C.; Klockgether,T.; Durr,A.; Chneiweiss,H.; Enczmann,J.; Farral,M.; Beckmann,J.; Mullan,M.; Wernet,P.; Agid,Y.; Freund,H-J.; Williamson, R.; Auburger,G.; Chamberlain,S.: Chromosomal assignment of the second locus for autosomal dominant cerebellar ataxia (SCA2) to chromosome 12q23-24.1.Nature Genetics 4:295, 1993.
  • Hernández,A.; Corral,L.; Muñiz,A.; Aláez,C.; Dorticós, E.; Martínez,G.; Hernández,P.: Lack of M-bcr rearrangement with b3a2 juntion revealed by polymerase chain reaction in a case of Philadelphia-positive intermediate lymphocytic lymphoma in leukemic phase. Brit.J.Haematol 82:626, 1992.
  • Hernández,A.; Corral,L.; Muñiz,A.; Aláez,C.; Espinosa,E.; Martínez,G.; Hernández,P.: Further evidence for the molecular heterogeneity of chronic myeloid leukaemia. Ann Hematol 62; 217, 1991
  • Hernández,A.; Corral,L.; Muñiz,A.; Aláez,C.; Martínez G.: LMC atípica con polimorfismo del gen BCR. Sangre, 36: 497, 1991.
  • Hernández,A.; Osterholz,J.; Price,C.M.; Wiedemann,L.M.; Gordon M.Y.; Goldman,J.M.; Morgan,G.J.: Detection of hybrid BCR/ABl messenger RNA in single CFU-GM colonies using the polymerase chain reaction. Experimental Hematology. 18:1142, 1990.
  • Morgan,G.; Hernández,A.; Chan,L.C.; Huges,T.; Martiat,T.; Wiedemann,L.M.: The role of alternative splicing patterns of BCR/ABL trancripts in the generation of the blast crisis of chronic myeloid leukaemia. British.J.Hematology 76:33, 1990.

Book chapter

  • Hernández, A.; Uhrberg, M.; Enczmann, J.; Witt, I.; Reitsma, R.; Wernet, P.: Rapid detection of point mutations in the protein C gene by temperature gradient gel electrophoresis. 25 Hämophilie-Symposion, Hamburg 1994, pg 147, editors Springer-Velag, Berlin, Heidelberg, New York, London, Paris, Tokyo, Hon Kong, Barcelona, Budapest.

Dr. Stephen B Channey

Regenerative and Preventive Medicine specialist

Stephen Channey is a leading Regenerative and Preventive Medicine specialist Dr. Channey is a graduate of the University of Richmond VA and St Georges University School of Medicine. Dr. Channey has a proven history of excellence in the medical field including:

  • 3 years private practice OB/GYN in Washington D.C.
  • 16 years OB/GYN Hospitalist at Memorial Regional Hospital Hollywood Florida
  • 10 years as Medical Director of Memorial Regional Hospitalist Group
  • 20 years experience providing hormone replacement therapy to Women and Men
  • More than 400 CME credits in study of natural and bioidentical hormone replacement therapy
  • Certified in Autologous Stem Cell Therapies
  • Certified by Worldlink Medical in BHRT

Dr. Channey is currently the Medical Director at Regenestem located at 9633 West Broward Blvd Suite 1 Plantation, FL 33324 and Medical Vitality Clinic located at 3860 Sheridan St. Suite B, Hollywood Florida 33021.

Dr. José Miguel Lopez Zepeda

Surgeon, Obstetrician, and Homeopathic Doctor

• Surgeon and Homeopath from the National School of Medicine and Homeopathy, National Polytechnic Medical Institute Mexico City, Mexico
• Master’s in Emotional Intelligence National Polytechnic Institute
• Master’s in NLP, Neurolinguistics Programming Mexican.
• Graduate Biomolecular Medicine. General Hospital of Mexico. 2002-2005.
• All Parenting Magazine
• Graduate in Classical Homeopathy from The International Academy of Classical Homeopathy, Alonnisos Greece in May 2011.
• Certified by the Ortho Institute of Healing Los Angeles California in the use of Platelet Rich Plasma and Stem Cells for joint injuries.
• MBA Health Institution La Salle University.
• Diploma in Physiotherapy from UNAM
• Certified in Ozone therapy at the Institute of Neurosurgery of Havana Cuba.
• Certified Stem cells, and certification by the ORTHOBIOLOGIC INSTITUTE in Los Angeles California.
• Certified in Prolotherapy by ORTHOBIOLOGIC Institute in Los Angeles California.
• Certified by REGENESTEM in handling extraction of multipotent cells, adipose tissue, peripheral blood and bone marrow. Miami Florida USA.
• Director of Health Protection Program and life PROSALVID Mexican Red Cross, Delegation León Gto.
• Advisory Council Member of the National School of Medicine and Homeopathy IPN
• He currently serves as Head of Education and Communication at the State Blood Transfusion Center of the Ministry of Health of Guanajuato
• Director of ORTHOCIMBIO Clinic and Research Center for Biomolecular Medicine based in León Gto.
• Diploma in Neural Therapy
• Diploma in Therapeutics with trace elements
• Diploma in Human Acupuncture complementary der Terapétuicas in the Mexican Association of Medical Acupuncturists, A B.C.
• Diploma in Homeopathy from the European Academy of Naturopathy ACENA, Malaga, Spain
• Diploma in Neuro Linguistic Programming. Mexican Institute of NLP.
• Diploma in Quantum Physics. Metabolic Mexican society. Dr. Sodi Pallares. Mexico DF.
• Diploma in cancer and terminal illnesses, by Dr. Hammer in Germany

Dr John P. Salerno

Dr. Salerno’s medical approach embraces the whole person – mind, body, and spirit – treating the entire person rather than just symptoms.

A best-selling author, Dr. Salerno’s medical expertise has given hope to hundreds in the field of complementary medicine, and has been featured in:

• Harper’s Bazaar
• Women’s Health
• Prevention Magazine
• First For Women
• OnFitness Magazine
• All Parenting Magazine
• Natural Awakenings

Dr. Salerno also served as a clinical preceptor at the Yale University School of Medicine (3 years), as Medical Director of St. Vincent’s Immediate Health Care in Shelton, Connecticut and lectured at the Vermont Family Practice Conference. His experience in family practice and urgent care makes him a versatile expert on the physiology and assessment of many complex medical conditions.

Dr. Salerno has developed and published The Silver Cloud Diet, a three-step approach to nutrition based on organic, unprocessed foods, low carbohydrate intake, and targeted supplement protocols. Most recently, his newly published books – The Salerno Solution: An Ounce of Prevention, A Lifetime of Health and Fight Fat With Fat, have helped thousands prevent disease and restore health. Although each book deals with various topics, the seamlessly blend together the importance of wholesome food recommendations with an emphasis on healthy lifestyle choices.

Always central to the idea of evidence based journalism, Dr. Salerno continuously reports of his exploratory findings in his own personal online newsletter, daily blogs, and related websites.

Dr. Rafael Moguel

Dr. Rafael Moguel Interventional Cardiologist Director Clinics of the Heart Born in Chiapas, México on October 30, 1959. Medicine school at Universidad Veracruzana in Veracruz, México (1985). Cardiology recidency at the Hospital 1° de Octubre, ISSSTE, Mexico City (1989). Pacemaker technology at Medtronic in Minneapolis, USA (1990). Hemodynamics at the Hospital 1° de Octubre, ISSSTE, Mexico City (1991). Interventional Cardiology at Hospital Clinic i Provincial in Barcelona Spain (1993). Core curriculum in carotid stenting (The Society for Cardiovascular Angiography and Interventions (SCAI). Atlanta GA, April 2005. Non-surgical Endovenous Laser Treatment (EVLT). Completion of training, DIOMED sponsored, December 2004. Head of Cath Lab. Hospital "1° de Octubre", ISSSTE, from 1998 through 2003. Assistant medical. Cardiology service. Unidad Cardiovascular, Hospital "1° de Octubre", ISSSTE, since 1991.

Actual director of Clinics of the Heart. Certified by the Mexican Council of Cardiology Fellow of the Society for Cardiac Angiography and Interventions (SCAI) Member of the main Mexican Societies of Cariology and Interventional Cardiology Member of the Latin American Society of Interventional Cardiology (SOLACI)

Charles F. Mahl, M.D., FACS, FICS, BCIM, CPT, CSN

Charles F. Mahl, M.D. maintains an active practice in regenerative medicine, preventive aging and pain therapies. His expertise includes prolotherapy, platelet rich plasma injections and Regenestem therapies.

A member of the Global Regenestem Group Scientific Advisory Board, Dr. Mahl sees Regenestem as medicine’s new frontier, offering unlimited possibilities for easing and even eliminating many forms of disease and injury-related pain. In fact, he views regenestem and regenerative medicine as the most important focus of research in medicine today.

After graduating from Case Western Reserve University in Cleveland, Ohio, Dr. Mahl earned his M.D. from the Rosalind Franklin School of Medicine in Chicago. He completed his residency and chief residency at Interfaith Hospital in New York, and completed a Vitreoretinal Fellowship at the University of Oregon. He maintained private practices in retinal-vitreous surgery from 1981 to 2000.

Dr. Mahl later completed a Fellowship program in anti-aging and regenerative medicine through the American Academy of Anti-aging Medicine and the Living Younger Preventive Aging Program. He is certified in age management medicine by The Cenegenics Education and Research Foundation.

He also completed a mentorship/preceptorship in prolotherapy and platelet rich plasma (PRP) with Alvin Stein, M.D. of Plantation, Florida, and is Regenestem-trained in both PRP and adipose/bone marrow derived Regenestem. Dr. Mahl is board certified in integrative medicine (BCIM), a certified sports trainer (CST) and a certified sports nutritionist (CSN). He is a member of multiple medical organizations and associations including the American Association of Orthopedic Medicine, and the American Osteopathic Association of Prolotherapy Regenerative Medicine, the American Society of Interventional Pain Management, the American Academy of Anti-Aging Medicine and the Age Management Medical Group.

He is a Fellow of the American College of Surgeons (FACS), a Fellow of the International College of Surgeons (FICS), and a physician volunteer with the Florida Reserve Medical Corps, FEMA, U.S. Department of Homeland Security.

Dr. Mahl operated his own medical practice focused on preventive aging, pain and regenerative medicine in Miami Beach from January 2010 to June 2014.

Since 2010 he has also served as medical consultant/associate in orthopedics at Extremity Preservation, an orthopedic surgery practice directed by Dr. Mark Sinnreich, M.D., Mount Sinai Hospital, Miami Beach. Dr. Mahl continues to practice at Extremity Preservation, and is currently licensed to practice medicine in Florida, New York, Kentucky, Indiana, California and Oregon.

Board certified by the American Sports and Fitness Association in sports nutrition and personal training, Dr. Mahl is a firm believer in the benefits of regenerative medicine and the alternatives to surgery and/or steroid injections that prolotherapy, PRP and Regenestem therapies provide. Dr. Mahl uses prolotherapy, PRP and regenestem to treat patients with tendon and ligament pain and injury to the neck, back, shoulders, elbows, wrists, hands, hips, knees, pubic symphysis, sacroiliac joints, ankles, feet, and even fingers and toes.

A popular international guest lecturer, Dr. Mahl speaks on a variety of regenerative medicine topics including cosmetic and aesthetic applications and the process of collecting and processing Regenestem from adipose tissue.

He belongs to numerous professional associations and organizations, including:

Age Management Medical Group
American Academy of Anti-Aging Medicine
American Association of Integrative Medicine
Integrative Practitioner Online Community
National Association of Physician Advisors
Physician Renaissance Network
American Association of Orthopedic Medicine
American Osteopathic Association of Prolotherapy and Regenerative Medicine
Florida Academy of Pain Medicine
International Hormone Society
European Society of Endocrinologists
American Society of interventional Pain Management

Dr. Mahldonates his time as a physician volunteer for South Florida Disaster Relief National Incident Management System (NIMS) Emergency Management Institute, FEMA, the U.S. Department Of Homeland Security, MRC Core Competencies Training, Institute For Disaster and Emergency Preparedness, Nova Southeastern University and Florida, Department of Health.

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